In a mixing bowl, combine ground turkey, breadcrumbs, beaten egg, 1/2 cup BBQ sauce, garlic powder, onion powder, salt, and pepper. Mix gently until just combined—do not overmix.
Form the mixture into 1-inch meatballs, about 20 total, and place them on a plate or tray.
Preheat your air fryer to 375°F (190°C) for 3 minutes.
Arrange meatballs in a single layer in the air fryer basket, ensuring they don’t touch.
Cook for 10-12 minutes, shaking the basket halfway through, until meatballs are golden brown and internal temperature reaches 165°F.
Brush meatballs with extra BBQ sauce during the last 2 minutes of cooking for a sticky glaze.
Let meatballs rest for 2 minutes before serving to lock in juices.